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January 25, 2016 by Luke Leave a Comment

Antioxidant intake from dietary and supplemental sources associated with improved atherogenic blood profile

A study reported in the journal Nutrients on January 4, 2016 found an association between total antioxidant capacity (TAC, a measure of antioxidants present in the diet) and reduced cardiovascular risk factors in adults.

Researchers at the University of Connecticut analyzed data from 4,039 men and women enrolled in the National Health and Nutrition Examination Survey (NHANES) 2007-2012. Total antioxidant intake from food and dietary supplements was calculated from subject responses to two 24-hour dietary recall questionnaires.

Tea, antioxidant supplements, vegetables, orange juice, berries and wine were the top contributors to total antioxidant capacity. Among subjects who used antioxidant supplements, total antioxidant capacity was 1.6 times higher than nonusers. Supplemental vitamin C accounted for 28% of total TAC, vitamin E for 2.1%, and flavonoids for 1.2% among users. Supplement users also consumed more antioxidants from food in comparison with those who did not use supplements.

Increased TAC from diet and supplements was associated with significantly lower triglycerides, triglycerides to high-density lipoprotein (HDL) cholesterol ratio, insulin resistance and inflammation, and an increase in high-density lipoprotein (HDL) cholesterol.

“Our findings support the hypothesis that an antioxidant-rich diet and intake of supplements are beneficial in reducing cardiovascular disease risk,” they conclude.

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