Luke Clarke

Functional Medicine Practitioner and Naturopath in Melbourne

Call US: 03 8820 0010
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March 9, 2017 by Luke Leave a Comment

Want to Look Younger and Healthier? Protect Those Telomeres

A book co-authored by a 2009 Nobel Prize winner biologist Elizabeth Blackburn  says that those shoelace-looking things at the end of your chromosomes determine how and when you begin to show signs of aging.

They may be why some people look and behave younger than others who are chronologically the same age.

In the new book, The Telomere Effect: A Revolutionary Approach to Living Younger, Healthier, Longer, biologist Elizabeth Blackburn and psychologist Elissa Epel detail ways the average Joe or Jane can protect their telomeres — and feel better.

Think positively. Practice meditation. Eat a plant-based diet. Get enough sleep. Exercise regularly..Such practices can slow down or even reverse the inevitable damage of aging.

Blackburn won the Nobel Prize for her work showing the role of telomeres in disease and aging. Telomeres, which have been likened to the cap at the end of a shoelace, protect the genetic material inside your DNA. People with longer telomeres have lower death rates from cancers and some diseases, but these telomeres tend to shorten as we age. Certain lifestyle factors also speed up their shortening.

Which is why Blackburn and Epel want to assure readers that there are steps to keep those telomeres long and sturdy.

“The telomeres are long and robust in healthier older people, and they’re more likely to get crumbled away and eroded away in people who are more susceptible to diseases at earlier ages,”

Not surprisingly, the telomere-protecting habits are what your mother most likley have long advised you to do. Think positively. Practice meditation. Eat a plant-based diet. Get enough sleep. Exercise regularly.. Such practices can slow down or even reverse the inevitable damage of aging.

“The world around us is incredibly important in its influence on our telomeres. That was one of the things that the research and lots of studies have found,”

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February 1, 2017 by Luke Leave a Comment

Did You Know?

  • Research from Circulation shows that women who consistently consume blueberries and strawberries have a 32 percent lower risk of heart disease.
  • Simply looking at photos of high-calorie foods can stimulate your brain’s reward center, thus weakening willpower.
  • 20 mg of iron a day can ease PMS symptoms.
  • Grunting or being vocal when lifting weights can increase muscle strength by eight percent.
  • The Mayo Clinic finds that people with a financial incentive to lose weight drop an average of seven more pounds than those with no monetary goal.
  • Mint gum can make fruit less appetizing.
  • According to Emotion, a trip down memory lane can actually make you feel physically warmer.
  • A five percent incline increase on the treadmill can burn 15 percent more calories.
  • Drinking alcohol can reduce the amount of antioxidants in your skin.
  • Women who religiously read nutrition labels weigh approximately nine pounds less than women who ignore those critical stats.
  • A shark’s cornea is so similar to a human’s that it has been used in eye surgery.
  • People read an average of 25 percent slower onscreen than on paper.
  • People tend to chew their food on the same side as their dominant hand. So if you are right-handed, you likely chew on the right side of your mouth.
  • After the age of 30, humans begin to gradually shrink in size.
  • Thinking about sex can double your pain threshold.
  • Every pound over your ideal weight can lower your life expectancy by 34 days. That means that a mere 15 pounds can cost you nearly 1.5 years of life!

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February 1, 2017 by Luke Leave a Comment

The New Silent Killer: Non-Alcoholic Fatty Liver Disease

As far as health threats are concerned, unless you’ve been diagnosed with a liver disease you probably don’t think too much about that particular organ. Heart disease and cancer tend to get the lion’s share of attention in newspapers and on TV. But as far as life-threatening diseases are concerned, non-alcoholic fatty liver disease—NAFLD for short—ranks as the worst of them all…and it’s becoming an epidemic.

NAFLD results when fat builds up in liver cells. The term non-alcoholic is used to separate the liver damage that occurs in alcoholics from those people who don’t drink excessive amounts of alcohol. The rise in the incidence of NAFLD goes hand-in-hand with the rise in the number of people who are overweight and obese. In fact, 80 percent of obese patients have NAFLD.

But you don’t have to carry extra pounds to get the disease. Even some lean people develop NAFLD. It affects 16 percent of people with a normal body mass index (BMI).

Even children and teens are developing NAFLD at an alarming rate. In one study, researchers found NAFLD in 14 percent of 564 children studied.

Over three timespans (1988-1994, 1999-2004 and 2005-2008), the prevalence of NAFLD doubled from 5.51 percent to 11 percent. Between 1988-1994, 46.8 percent of all chronic liver diseases were related to NAFLD, but by 2005-2008, this number had skyrocketed to 75.1 percent. By the year 2030, the prevalence of NAFLD in Australia is expected to rise by another 50 percent.

A Stealthy Enemy

The scary part is that NAFLD often has no symptoms until it has progressed to the point where it’s more difficult to reverse with behavior changes, such as exercise and an improved diet. It’s often discovered accidentally when routine liver tests show elevated liver enzymes. And there’s no medication that can treat the disease, although in its earliest stages, weight loss and dietary changes can help.

If NAFLD is left unchecked, it can progress into non-alcoholic steatohepatitis (NASH). This results in cirrhosis marked by scarring of the liver known as fibrosis that is as severe as the damage caused by alcoholism. At this stage, people who suffer from NASH can experience symptoms such as jaundice, stomach pain, swelling of the legs and fatigue.

What’s to Blame for NAFLD?

Being overweight or obese is at the top of the list for risk factors of NAFLD. Even just having a big belly can up your risk, too. Belly fat—known as central obesity—is a sign that visceral fat is developing on your organs. Visceral fat, otherwise known as intra-abdominal fat, is sandwiched between your internal organs and your torso. It’s this type of fat that’s linked to many health concerns, including NAFLD. Visceral fat triggers chronic, low-grade inflammation, which contributes to liver injury.

Central obesity is a hallmark of metabolic syndrome, a cluster of risk factors for heart disease that also includes high blood pressure, high triglycerides, high blood sugar and low HDL “good” cholesterol. If you have metabolic syndrome, you’re also at increased risk for NAFLD.

Fructose and Sugar—Guilty as Charged

Researchers have found that drinking beverages sweetened with high-fructose corn syrup increases the production of lipids, disturbs insulin sensitivity and increases central obesity in overweight or obese adults, all of which are problems that can lead to NAFLD.

Studies also have found that people who have NAFLD eat and drink more fructose compared to people without the disease. And consuming fructose is associated with more severe NAFLD.

Eating lots of snacks high in fat and sugar also tips the scales in favor of fatty liver. In a six-week study of lean men fed either a high-calorie diet that included high-fat/high-sugar drinks between meals, a high-calorie diet with high-sugar drinks between meals or a balanced diet without between-meal snacks, scientists found that belly fat increased in the high-fat/high-sugar group and in the high-sugar-frequency group.

Liver insulin sensitivity also decreased in the high-fat/high-sugar-frequency group. Plus, triglyceride levels rose in the liver of the subjects consuming the high-fat/high-sugar snacks and the subjects consuming only the high-sugar snacks. The changes were independent of caloric content and body weight gain.

Even Lean People Aren’t Safe

Although being overweight or obese is the primary risk factor of NAFLD, it’s not the only one. That may explain why some people who are lean develop the disease. In fact, many of these normal-weight NAFLD patients don’t have any of the classic risk factors for NAFLD, such as diabetes, hypertension, high triglycerides, low high-density-lipoprotein cholesterol, central obesity and metabolic syndrome.

Other Risk Factors

Besides obesity, genetic predisposition is another risk factor for NAFLD. This might offer an explanation as to why some lean people get the disease. It’s possible that the lean people in the study mentioned above had what’s known as a lisosomal acid lipase deficiency. This deficiency lowers levels of an enzyme that helps break down lipids and triglycerides, causing fat to accumulate.

These days, your liver is working overtime thanks to all the toxins it’s exposed to from the environment. The liver is responsible for detoxifying these environmental chemicals.

This adds to the liver’s total burden and may make it more vulnerable to disease. Some environmental chemicals such as bisphenol-A (BPA) are directly linked to weight gain and harmful changes in the liver. In obese male children, BPA was linked to elevated levels of the liver enzyme aspartate aminotransferase and high diastolic blood pressure.

Do You Have NAFLD?

If there is a suspicion you have NAFLD, you need to test your liver enzymes, along with your triglyceride and cholesterol levels. If the tests come back abnormal, you  may also order an abdominal ultrasound. A liver biopsy—considered the gold standard for diagnosing NAFLD—also is a possibility.

The good news is that the sooner you’re diagnosed with the disease, the easier it is to control. And even if you don’t have NAFLD, if you’re overweight, now is a good time to put into practice some of the following suggestions before it’s too late.

Lifestyle Solutions

If you’re overweight, start a daily exercise routine and watch what you eat. Not surprisingly, eating anything that causes you to pack on the pounds, especially in your abdominal region, will increase your risk of NAFLD.

To make a difference in your liver’s health, you’ll need to lose three to 10 percent of your body weight.

Even if you’re not overweight, daily exercise comes with a whole slew of benefits that have nothing to do with weight loss, including protecting the health of your liver.

Eat lots of vegetables, fruit, nuts and fish high in omega-3s such as salmon. Studies have shown there’s an association between diets low in vitamin C, vitamin K, folate and omega-3 fatty acids and an increased risk of NAFLD

Avoid sugar and high fructose corn syrup. As noted earlier, they’re linked to central obesity and increased levels of triglycerides, as well as other changes that might lead to NAFLD.

 

Two Liver-Healthy Supplements

As you’re losing weight, be certain to eat lots of fiber and take a good detoxification supplement. During weight loss, all the environmental toxins that were stored in fat cells are released into the body and sent to the liver, which is already working overtime to fight off the inflammation and other harmful changes associated with being overweight.

When it comes to NAFLD specifically, berberine is an ideal choice. In type 2 diabetic patients with NAFLD, berberine supplementation improved the results of a liver ultrasound, lowered liver enzymes, triglyceride levels and LDL “bad” cholesterol, while raising levels of HDL “good” cholesterol.

Vitamin D3 is another important nutrient for anyone who’s at risk for NAFLD. People who have NAFLD have lower levels of this vitamin compared to people who don’t have the disease, leading researchers to believe low vitamin D levels might make a person more vulnerable to NAFLD. This same association with low vitamin D levels is found in NAFLD patients who have normal total body fat, indicating that vitamin D deficiency might make even some lean people susceptible to the disease.

Fighting Fatty Liver

Non-alcoholic fatty liver disease is a threat that’s easy to fight—if you catch it soon enough. That’s why it’s important to act now. Begin a daily exercise routine and toss out the cookies, baked goods and soft drinks that are lingering around your house. And consider supplementing with berberine and vitamin D3.

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February 1, 2017 by Luke Leave a Comment

Too Much Sitting, Too Little Exercise May Accelerate Biological Aging

Researchers at University of California San Diego School of Medicine report that elderly women who sit for more than 10 hours a day with low physical activity have cells that are biologically older by eight years compared to women who are less sedentary.

The study, publishing online January 18 in the American Journal of Epidemiology, found elderly women with less than 40 minutes of moderate-to-vigorous physical activity per day and who remain sedentary for more than 10 hours per day have shorter telomeres — tiny caps found on the ends of DNA strands, like the plastic tips of shoelaces, that protect chromosomes from deterioration and progressively shorten with age.

As a cell ages, its telomeres naturally shorten and fray, but health and lifestyle factors, such as obesity and smoking, may accelerate that process. Shortened telomeres are associated with cardiovascular disease, diabetes and major cancers.

This study found cells age faster with a sedentary lifestyle. Chronological age doesn’t always match biological age.

Nearly 1,500 women, ages 64 to 95, participated in the study. The women are part of the larger Women’s Health Initiative (WHI), a national, longitudinal study investigating the determinants of chronic diseases in postmenopausal women. The participants completed questionnaires and wore an accelerometer on their right hip for seven consecutive days during waking and sleeping hours to track their movements.

“It was found that women who sat longer did not have shorter telomere length if they exercised for at least 30 minutes a day,

“Discussions about the benefits of exercise should start when we are young, and physical activity should continue to be part of our daily lives as we get older, even at 80 years old.”

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November 18, 2016 by Luke Leave a Comment

Do you suffer From IBS? – Then This May Interest You

Are you one of the thousands of people in Australia who suffers from IBS? (Irritable Bowel Syndrome)

Have you tried to treat your IBS to no avail?

Do you have digestive issue?… pain, bloating, gas, constipation, diarrhea… ?

Do you find that you feel bloated and uncomfortable after the consumption of starchy carbohydrates?

The leading cause of IBS is SIBO and it is estimated that greater than 60% of IBS cases are caused by SIBO.

Just attended the first conference held in Australia for SIBO (small Intestinal bacterial overgrowth)

What is SIBO ( Small Intestinal Bacterial Overgrowth)

Simply put, Small Intestine Bacterial Overgrowth is a chronic bacterial infection of the small intestine. The infection is of bacteria that normally live in the gastrointestinal tract but have abnormally overgrown in a location not meant for so many bacteria.

The Problem

The bacteria interfere with our normal digestion and absorption of food and are associated with damage to the lining or membrane of the Small Intestine (leaky gut syndrome)

  • They consume some of our food which over time leads to deficiencies in their favorite nutrients such as iron and B12, causing anemia.
  • They consume food unable to be absorbed due to SI lining damage, which creates more bacterial overgrowth (a vicious cycle).
  • After eating our food, they produce gas/ expel flatus, within our Small Intestine.  The gas causes abdominal bloating, abdominal pain, constipation, diarrhea or both (the symptoms of IBS).  Excess gas can also cause belching and flatulence.
  • They decrease proper fat absorption leading to deficiencies of vitamins A & D and fatty stools.
  • Through the damaged lining, larger food particles not able to be fully digested, enter into the body which the immune system reacts to.  This causes food allergies/ sensitivities.
  • Bacteria themselves can also enter the body/bloodstream.  Immune system reaction to bacteria and their cell walls (endotoxin) causes chronic fatigue and body pain and burdens the liver.
  • Finally, the bacteria excrete acids which in high amounts can cause neurological and cognitive symptoms.

 The Solution

SIBO Testing

Unfortunately there is no perfect test. The small intestine (SI) is a hard place to get to. If we want to see or sample the SI, endoscopy only reaches into the top portion, and colonoscopy only reaches into the end portion. The middle portion, which is substantial (about 17 feet) is not accessible, other than by surgery. And stool testing predominantly reflects the large intestine (LI).

Luckily, there is a non-invasive test which is commonly used in SIBO research; the Hydrogen/Methane Breath Test.

SIBO Treatment.

Commonly, treatment involves the following strategy..

  • Reduce the bacteria.  Options include, Antibiotics, Herbal Antibiotics and  Diet
  • Improve digestive motility, the natural expulsion of bacteria in to the large intestine.
  • Heal the Small Intestine lining.   Occurs on it’s own with bacteria reduced, assisted by diet and optional supplements.
  • Prevent relapse.

If this sounds like you, there is much that can be done to assess, treat and maintain your digestive health.

 

 

 

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Luke Clarke

Phone: (03) 8820 0010

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Ashburton VIC 3147, Australia
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